Fenomenul de bounce PSA dupČ brahiterapia prin implant permanent cu I în cancerul de prostată localizat - factori de predicţie clinici şi dozimetrici.
Source: Romanian Journal of Urology. Dec, Vol. Author s : Hăineală, B. Guler; Sinescu, I. Abstract: Introduction and Objectives: The purpose of the study is to evaluate the incidence, time of occurrence and magnitude of PSA bounce phenomenon BP after permanent prostate implant with Prostate cancer stages t1c, clinical and dosimetric factors favoring the occurrence of this phenomenon and its impact on biochemical relapse.
- Olinici is cell cycle and his implication in oncology.
- Cancer de prostată
Prostate cancer stages t1c and Methods: Between October - July were treated with permanent prostate implant with I a total of patients with prostate cancer, alone in stage T1c-T2a. PSA bounce is defined as a temporary increase in PSA value followed by a consecutive decrease recorded with the same value before the increase or a lower value.
PSA bounce phenomenon was recorded in 31 patients Results: The average magnitude's bounce was 1. Mean PSA at 12 months for patients on monotherapy who did not show bounce phenomenon was 0. For patients who showed no BP average D90 was Initial PSA values, Gleason score, preoperative prostate volume did not affect this process.
Conclusions: PSA bounce is not a rare phenomenon after prostate brachytherapy and should be always considered whenever we have a patient with rising PSA after implant, especially when the perioud of time that has passed since the procedure is not long.
It occurs more frequently in younger patients and is not related to preoperative clinical and dosimetry factors.
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