Free psa total psa ratio cancer, CANCER PROSTATIC LOCALIZAT

PSA este prezent in cea mai mare parte a sa in lichidul seminal, dar o mica parte din antigenul specific prostatic se afla si in sange. Testul PSA masoara nivelul in sange al acestui antigen. Cand exista unele boli, cum este prostata marita sau inflamata, in circuitul sangvin ajunge mai mult PSA. Nivelul PSA se masoara si pentru a monitoriza raspunsul la tratament al persoanelor care au fost diagnosticate cu cancer de prostata.

Cuvinte cheie hiperplazie benignă de prostată IRM multiparametrică cancer de prostată PI-RADS imagistică medicală Introduction Benign prostatic hyperplasia BPH is a histologic diagnosis characterized by proliferation of the prostatic cellular elements. Benign hyperplastic nodules are most commonly seen in the transition zone, but they can also protrude into the peripheral zone or even beyond the prostatic capsule, appearing as an exophitic pelvic mass or as a mass within the bladder 2.

Teste de laborator

Usually, there is a direct relationship between prostate enlargement and symptoms severity, although many patients with small prostates also present urinary obstruction, because of the strategically position of the adenoma, sitting right on the bladder outlet 2. The initial evaluation should asses the frequency and severity of symptoms by using the International Prostate Symptom Score IPSS 4 and it should also include a digital rectal examination and urinalysis.

Enlargement of the prostate associated with a palpable nodule and elevated PSA prostate specific antigen level requires imaging methods of diagnosis, such as transrectal ultrasonography which provides a more accurate assessment of prostate volume than digital rectal examination does 5 and MRI for the characterization of the prostatic tissue, due to its excellent contrast resolution.

Vă recomandăm să contactaţi recepţia pentru mai multe informaţii. Informaţii generale şi recomandări pentru determinarea free-PSA Antigenul specific prostatic PSA este un component esenţial al plasmei seminale, având o greutate moleculară de 33 kDa. Este sintetizat în celulele acinare şi în epiteliul ductal al prostatei sub controlul hormonilor androgeni testosterondihidrotestosterondupă care este secretat în sistemul ductal unde atinge concentraţii mari.

Case report We present the case of a year-old patient who was referred to the urology department of our clinical institute three years ago, with lower urinary tract symptoms LUTS. PSA value was Digital rectal examination and transrectal ultrasonography revealed an increased prostate.

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The patient was directed to our department, where we performed an MRI investigation, in order to rule out prostate cancer, possibly associated with BPH. A written consent was taken from the patient before entering the scanner room, after he was interviewed about his medical history, possible allergies, previous examinations and MRI free psa total psa ratio cancer.

An intravenous antispasmodic agent is routinely used, in order to decrease the artifacts generated by intestinal motility, after a venous line is secured.

Pachete de analize medicale

He was investigated on a Toshiba 1. High-resolution multiplanar T2 WI are morphological sequences ideal for the prostate anatomy evaluation.

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Dynamic contrast enhancement DCE and diffusion-weighted DWI are functional sequences, corresponding to angiogenesis and cellular density, respectively. MR-spectroscopy MRS is another functional sequence that correlates with cellular turnover, but we do not perform it routinely.

  • Clisma caldă pentru prostatită
  • Scopul depistarii precoce a cancerului de prostata este identificarea cancerului intr-un moment in care tratamentul este cel mai probabil eficient.
  • Раздался еще один выстрел.
  • Azitromicina para la prostatitis dosis

The scanning protocol is listed in Table 1. Contrast media is injected in a volume of 0. Table 1.

  • Dacă doare partea inferioară a spatelui cu prostatita
  • Хейла нигде не было .
  • ГЛАВА 107 Сьюзан понятия не имела, сколько прошло времени.
  • Tratamentul consecințelor prostatitei

The routine free psa total psa ratio cancer MRI protocol for prostate imaging used for the patient Imaging findings showed an enlarged prostate, with its three diameters of 51 mm, 61 mm and 41 mm longitudinal diameter, axial diameter and anteroposterior diameter, respectivelywith an estimated total volume of The transitional zone TZ appeared asymmetrically enlarged, predominantly on the right half of the prostate, which led to the compression of the urethra being displaced to the left and thinning the peripheral zone PZespecially on the right side of the base.

The PZ showed diffuse decreased signal intensity on T2WI and no restricted diffusion, typical aspect for chronic inflammatory lesions.

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The TZ presented multiple small cystic areas and a multinodular structure because of the presence of stromal and glandular nodulesthe biggest one being located in the right middle third and apex of the TZ, with an axial diameter of 38 mm. We noticed a bulging aspect of the macronodule described in the right TZ, protruding into the neighboring PZ, with a central area of increased signal intensity on diffusion WI and decreased signal intensity on ADC map, but a negative dynamic contrast enhancing DCE curve Figures free psa total psa ratio cancer and 2.

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Figure 1. This particular right TZ nodule has been marked with a final PI-RADS score of 3, which means that the presence of clinically significant cancer is equivocal.

Case Report

Discussion BPH nodules appear as a mixture of signal intensities, ranging from hypointense to hyperintense on T2 WI, depending on the proportion of their stromal and glandular components.

They are well-delineated nodules that arise in the TZ, involving the periurethral regions, but sometimes they can bulge the surgical capsule, so they can be found in the PZ.

The patient was referred for prostatic biopsy one month after the MR examination, considering the elevated PSA value, which revealed a benign appearance of the sample: polymorphic aspect on account of a chronic inflammatory, non-specific process.

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Retrospectively, we can conclude that DWI changes and elevated PSA value may be due to this chronic inflammatory, non-specific process. The patient received anti-inflammatory treatment and remained under urological surveillance. Conclusions Multiparametric MRI is a precious tool in prostate tissue characterization, completing clinical and biological information, but in case of BPH, a suspected prostate carcinoma in the TZ may represent a real challenge for the radiologist.

Această modaliatate terapeutică este posibilă numai prin colaborarea în cadrul unei echipe mixte formate din urolog, radioterapeut şi un fizician medical. Această metodă implică plasarera unor surse seed de Iodîn interiorul glandei prostatice, după un plan bine stabilit. Scopul principal al acestei lucrări îl reprezintă urmărirea pe termen mediu şi lung al rezultatelor oncologice, acest lucru realizându-se în special prin monitorizarea valorilor PSA prostate specific antigen. Modificările biochimice ale PSA urmează o dinamică diferită decât cele apărute în cazul altor proceduri, cum ar fi radioterapia externă sau prostatectomia radicală.

Often, biopsy is mandatory for a definitive differentiation between inflammatory lesions and prostate cancer.

Bibliografie Lim KB. Epidemiology of clinical benign prostatic hyperplasia.

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Asian J Urol. Foo KT. Diagnosis and treatment of benign prostate hyperplasia in Asia. Transl Androl Urol. Emberton M, et al.

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